Direct N-Me Aziridination of Enones

Jawahar Lal Jat, Ajay K. Yadav, Chandra Bhan Pandey, Dinesh Chandra and Bhoopendra Tiwari*

J. Org. Chem. 2022, 87, 3751-3757


Metal-free synthesis of secondary amides using N-Boc-O-tosylhydroxylamine as nitrogen source via Beckmann rearrangement

Jawahar Lal Jat, Puneet Kumar, Soumya Verma, Dinesh Chandra, Vikram Singh and Bhoopendra Tiwari*

New. J. Chem. 2022, DOI: 10.1039/D2NJ02755K


Metal and Additive-Free Intermolecular Aziridination of Olefins Using N-Boc-O-Tosylhydroxylamine

Jawahar Lal Jat, Dinesh Chandra,  Vikram Singh, Puneet Kumar and Bhoopendra Tiwari*

Synthesis, 2022, DOI: 10.1055/a-1879-7974


Catalytic Enantioselective Syn-Hydroxy-Oxyacylation of Electron Deficient Alkenes

Chandra Bhan Pandey, Vikram Singh, Susanta Ghanta and Bhoopendra Tiwari*

ChemRxiv 2021, DOI: 10.26434/chemrxiv.14345981.v2


A General Method for α-Oxyacylation of Vinyl Ketones Using Koser’s Reagent

Chandra Bhan Pandey, Bal Krishna Mishra, Tazeen Azaz, Hemlata Mourya, Bali Ram and Bhoopendra Tiwari*

J. Org. Chem. 2021, 86, 12277-12284


Carbene Catalyzed Access to 3,6-Disubstituted α-Pyrones via Michael Addition/Lactonization/Elimination Cascade

Anil Kumar Khatana, Vikram Singh, Manoj Kumar Gupta and  Bhoopendra Tiwari* 

Adv. Synth. Catal. 2021, 363, 4862-4865


Stitching Triazoles to Arenes via a Transition Metal-Free Aryne Diels-Alder/1,3-Prototropic Shift/Dehydrobromination Cascade

Ranadeep Talukdar, Vikram Singh, Hemlata Mourya, Malik Nassibullah and  Bhoopendra Tiwari* 

J. Org. Chem. 2021, 86, 12277-12284


Fe(II)-Catalyzed Synthesis of Unactivated Aziridines (N-H/N-Me) from Olefins Using O-Arylsulfonyl Hydroxylamines

Dinesh Chandra, Ajay K. Yadav, Vikram Singh, Bhoopendra Tiwari*, Jawahar L. Jat*

Chem. Select  2021, 06, 10524-10526


Access to enantioenriched 4-phosphorylated δ-lactones from β-phosphorylenones and enals via carbene organocatalysis

Ram Subhawan Verma, Anil K. Khatana, Monika Mishra, Shailesh Kumar and  Bhoopendra Tiwari* 

Chem. Commun. 2020, 56, 7155-7158


Stereoselective Oxidative Rearrangement of Di-Substituted Unactivated Alkenes Using Hypervalent Iodine(III) Reagent

Chandra Bhan Pandey, Tazeen Azaz, Ram S. Verma, Monika Mishra,  Jawahar L. Jat and  Bhoopendra Tiwari*

 J. Org. Chem. 2020, 85, 10175-10181


Global Access to 3/4-Phosphorylated Heterocycles via a Carbene-Catalyzed Stetter Reaction of Vinylphosphonates and Aldehydes

Ram Subhawan Verma, Monika Mishra, Chandra Bhan Pandey and  Bhoopendra Tiwari*  

J. Org. Chem. 2020, 85, 8166-8175

Abstract Image


Direct synthesis of secondary amides from ketones through Beckmann rearrangement using O-(mesitylsulfonyl)hydroxylamine

Dinesh Chandra, Soumya Verma, C. B.  Pandey, A. K. Yadav, P. Kumar, Bhoopendra Tiwari*, Jawahar L. Jat*,

Tetrahedron Lett. 2020, 61, 151822-151826


Zinc(II)-Catalyzed Synthesis of Secondary Amides from Ketones via Beckmann Rearrangement Using Hydroxylamine-O-sulfonic Acid in Aqueous Media

Soumya Verma, P. Kumar, Anil K. Khatana, D. Chandra, A. K. Yadav, Bhoopendra Tiwari* and Jawahar L. Jat*

Synthesis, 2020, 85, 8166-8175 [ Invited Contribution]


Carbene/Base-Mediated Redox Alkenylation of Isatins using β-Substituted Organoselenones and Aldehydes

Atanu Bhaumik, Tazeen Azaz, Vikram Singh, Anil K. Khatana and  Bhoopendra Tiwari*

J. Org. Chem. 2019, 84, 14898-14903

Abstract Image


Construction of Phenanthrenes and Chrysenes from β-Bromovinylarenes via Aryne Diels–Alder Reaction/Aromatization

Vikram Singh, Ram Subhawan Verma, Anil K. Khatana and  Bhoopendra Tiwari*

J. Org. Chem. 2019, 84, 14161-14167

Abstract Image


Direct N-H/N-Me Aziridination of Unactivated Olefins Using O-(Sulfonyl)hydroxylamines as Aminating Agents

Shekh Shabir, Chandra Bhan Pandey, Ajay K. Yadav, Bhoopendra Tiwari* and Jawahar L. Jat*

J. Org. Chem. 2018, 83, 12255-12260

Abstract Image


A Highly Efficient NHC-Catalyzed Aerobic Oxidation of Aldehydes to Carboxylic Acids

Anil K. Khatana, Vikram Singh, Manoj Kumar Gupta and Bhoopendra Tiwari*

Synthesis 2018, 50, 4290-4294 [ Invited Contribution]


Carbene-Catalyzed Tandem [1,2]-Phospha-Brook/[1,4]-Phosphate Rearrangement: Access to α-Ketophosphates via Controlled Cross-Acyloin Condensation

Ram Subhawan Verma, Chandra Bhan Pandey, Shailesh Kumar and Bhoopendra Tiwari*

J. Org. Chem. 2018, 83, 9478-9483

Abstract Image


Direct Construction of 2,3-Dihydroxy-2,3-diaryltetrahydrofurans via N-Heterocyclic Carbene/Base-Mediated Domino Reactions of Aromatic Aldehydes and Vinyl Selenone

Atanu Bhaumik, Ram Subhawan Verma and Bhoopendra Tiwari*

Org. Lett. 2017, 19, 444–447

Abstract Image


Catalytic Activation of Carbohydrates as Formaldehyde Equivalents for Stetter Reaction with Enones

J. Zhang, C. Xing, B. Tiwari, Y. R. Chi

J. Am. Chem. Soc. 2013, 135, 8113–8116 [The Most read article of June 2013]

Abstract Image


Asymmetric Access to the Smallest Enolate Intermediate via Organocatalytic Activation of Acetic Ester

S. Chen, L. Hao, Y. Zhang, B. Tiwari, Y. R. Chi

Org. Lett. 2013, 15, 5822–5825

Abstract Image


Organocatalytic Activation of α-Alkyl Carboxylic Esters as Enolate Precursors to React with α,β-Unsaturated Imines

L. Hao, S. Chen, J. Xu, B. Tiwari, Z. Fu, Y. R. Chi

Org. Lett. 2013, 15, 4956-4959

Abstract Image


Controlled β-protonation and [4+2] cycloaddition of enals and chalconesvia N-heterocyclic carbene/acid catalysis: toward substrate independent reaction control

Z. Fu, H. Sun, S. Chen, B. Tiwari, G. Li, Y. R. Chi

Chem. Commun. 2013, 49, 261–263 [Highlighted in Synfacts]

Graphical abstract: Controlled β-protonation and [4+2] cycloaddition of enals and chalcones via N-heterocyclic carbene/acid catalysis: toward substrate independent reaction control


Direct α-Functionalization of Simple Aldehydes via Oxidative N-Heterocyclic Carbene Catalysis

J. Mo, R. Yang, X. Chen, B. Tiwari, Y. R. Chi

Org. Lett. 2013, 15, 50–53 [Among top 5 most read articles of the month]

Abstract Image


Enantioselective Oxidative Cross‐Dehydrogenative Coupling of Tertiary Amines to Aldehydes

J. Zhang, B. Tiwari, C. Xing, X. Chen, Y. R. Chi

Angew. Chem. Int. Ed. 2012, 51, 3649–3652



Facile Access to Chiral Ketones through Metal-free Oxidative C-C Bond Cleavage of Aldehydes by O2

B. Tiwari, J. Zhang, Y. R. Chi

Angew. Chem. Int. Ed. 2012, 51, 1911–1914



Highly Enantioselective Addition of Enals to Isatin-Derived Ketimines Catalyzed by N-Heterocyclic Carbenes: Synthesis of Spirocyclic γ-Lactams

H. Lv, B. Tiwari, J. Mo, X. Chong, Y. R. Chi

Org. Lett. 2012, 14, 5412–5415 [Highlighted in Synfacts]

Abstract Image


Enantioselective Intramolecular Formal [2+4] Annulation of Acrylates and α,β- Unsaturated Imines Catalyzed by Amino Acid-Derived Phosphines

Z. Jin, R. Yang, Y. Du, B. Tiwari, R. Ganguly, Y. R. Chi

Org. Lett. 2012, 14, 3226–3229

Abstract Image


Access to Spirocyclic Oxindoles via N-Heterocyclic Carbene-Catalyzed Reactions of Enals and Oxindoles-Derived α,β-Unsaturated Imines

K. Jiang, B. Tiwari, Y. R. Chi

Org. Lett. 2012, 14, 2382–2385

Abstract Image


Addition of Indoles to Oxyallyl Cations for Facile Access to α-Indole Carbonyl Compounds

Q. Tang, X. Chen, B. Tiwari, Y. R. Chi

Org. Lett. 2012, 14, 1922–1925

Abstract Image


Synthesis of the C10-C24 fragment of (+)-Cannabisativine

S. Chandrasekhar, B. Tiwari

Tetrahedron: Asymmetry 2009, 20, 1924–1929


Chiral pyrrolidine-triazole conjugate catalyst for asymmetric Michael and Aldol reactions

S. Chandrasekhar, B. Tiwari, B. B. Parida, C. R. Reddy

Tetrahedron: Asymmetry 2008, 19, 495–499


Asymmetric synthesis of a protected dihydroxy piperazic acid derivative

S. Chandrasekhar, G. Parimala, B. Tiwari, C. Narsihmulu, G. D. Sarma

Synthesis 2007, 11, 1677–1682


Concise synthesis of truncated pachastrissamine (jaspine B) and its enantiomer

S. Chandrasekhar, B. Tiwari, S. J. Prakash

ARKIVOC 2006, (xi), 155–159




Methods of preparing chiral Ketones from aldehydes

B. Tiwari, Y. R. Chi, PCT Int. Appl. (2013), WO 2013095301 A1 20130627